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Nimustine hydrochloride (ACNU) is a DNA cross-linking and DNA alkylating agent, which induces DNA replication blocking lesions and DNA double-strand breaks. Nimustine hydrochloride inhibits DNA synthesis, it is commonly used in chemotherapy for glioblastomas.
Oncotarget. 2015 Oct 20;6(32):33755-68.
Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM
Nimustine hydrochloride purchased from AbMole
| Molecular Weight | 309.15 |
| Formula | C9H14Cl2N6O2 |
| CAS Number | 55661-38-6 |
| Solubility (25°C) | DMSO ≥ 50 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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