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Myristoleic acid

Cat. No. M21514
Myristoleic acid Structure
Size Price Availability Quantity
100mg USD 585  USD585 In stock
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Quality Control & Documentation
Biological Activity

Myristoleic acid is a tedecaenoic acid with double bonds at positions 9-10 and a Z configuration. Myristoleic acid, a cytotoxic component of Serenoa repens extract, can induce apoptosis and necrosis of human prostatic cells.

Chemical Information
Molecular Weight 226.35
Formula C14H26O2
CAS Number 544-64-9
Solubility (25°C) N/A
Storage -20°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Yong-Guy Kim, et al. Phytomedicine. Antibiofilm activities of fatty acids including myristoleic acid against Cutibacterium acnes via reduced cell hydrophobicity

[2] Youn Kyung Choi, et al. Biomol Ther (Seoul). Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells

[3] Lin-Hu Quan, et al. Gut. Myristoleic acid produced by enterococci reduces obesity through brown adipose tissue activation

[4] Jun-Oh Kwon, et al. Eur J Pharmacol. Myristoleic acid inhibits osteoclast formation and bone resorption by suppressing the RANKL activation of Src and Pyk2

[5] K Iguchi, et al. Prostate. Myristoleic acid, a cytotoxic component in the extract from Serenoa repens, induces apoptosis and necrosis in human prostatic LNCaP cells

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Keywords: Myristoleic acid supplier, Apoptosis, inhibitors, activators

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