All AbMole products are for research use only, cannot be used for human consumption.
MRT68921 dihydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.
| Molecular Weight | 507.5 |
| CAS Number | 2080306-21-2 |
| Solubility (25°C) | Water 31.25 mg/mL |
| Storage | 2-8°C, dry, sealed |
| Related ULK Products |
|---|
| XST-14
XST-14 is a potent, competitive and highly selective ULK1 inhibitor with an IC50 of 26.6 nM. XST-14 induces autophagy inhibition by reducing the phosphorylation of the ULK1 downstream substrate. XST-14 has antitumor effects. |
| DCC-3116
DCC-3116 is an orally active ULK1/2 inhibitor. |
| DCC-3116
DCC-3116 is a first-in-class, potent and selective inhibitor of ULK1/2 kinases and autophagy. ULK1/2 are kinases that receive and process input from nutrient and stress sensors to initiate autophagy. |
| MRT68921
MRT68921 is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. |
| SBP-7455
SBP-7455 is a dual-Specific ULK1/2 autophagy inhibitor with IC50s of 13 nM and 476 nM for ULK1 and ULK2 in ADP-Glo assay, respectively. |
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