ULK UNC-51-like kinase

Inhibitors

Cat.No.	Name	Information
M21036	SBP-7455	SBP-7455 is a dual-Specific ULK1/2 autophagy inhibitor with IC50s of 13 nM and 476 nM for ULK1 and ULK2 in ADP-Glo assay, respectively.
M21031	BL-918	BL-918 is a potent, orally active activator of UNC-51-like kinase 1 (ULK1) with EC50 of 24.14 nM and Kd of 0.719 μM. BL-918 induces cytoprotective autophagy for Parkinson's disease treatment.
M13577	MRT68921 dihydrochloride	MRT68921 dihydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.
M13576	LYN-1604 dihydrochloride	LYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC).
M10323	ULK-101	ULK-101 is a potent and selective ULK1 inhibitor with in vitro IC50 of 8.3 nM.
M10069	LYN-1604 2HCl	LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.