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MMV688845

Cat. No. M29355

All AbMole products are for research use only, cannot be used for human consumption.

MMV688845 Structure
Synonym:

(R)-GSK1729177A

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Quality Control & Documentation
Biological Activity

MMV688845 is a nontuberculous mycobacteria (NTM) RNA polymerase inhibitor with bactericidal activity against Mycobacterium abscessus and anti-tuberculosis efficacy.

Chemical Information
Molecular Weight 435.54
Formula C24H25N3O3S
CAS Number 2208962-35-8
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Markus Lang, et al. J Med Chem. Synthesis and Characterization of Phenylalanine Amides Active against Mycobacterium abscessus and Other Mycobacteria

[2] Lea Mann, et al. Microbiol Spectr. In Vitro Profiling of the Synthetic RNA Polymerase Inhibitor MMV688845 against Mycobacterium abscessus

[3] Lea Mann, et al. Amino Acids. Racemization-free synthesis of Nα-2-thiophenoyl-phenylalanine-2-morpholinoanilide enantiomers and their antimycobacterial activity

[4] Jinsun Jeong, et al. PLoS One. Pathogen Box screening for hit identification against Mycobacterium abscessus

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  Catalog
Abmole Inhibitor Catalog




Keywords: MMV688845, (R)-GSK1729177A supplier, DNA/RNA Synthesis, inhibitors, activators

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