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ML402 

Cat. No. M29858

All AbMole products are for research use only, cannot be used for human consumption.

ML402  Structure

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Quality Control & Documentation
Biological Activity

ML402, a thiophene-carboxamide, is a selective K2P2.1(TREK-1) and K2P10.1(TREK-2) activator. ML402 is inactive against K2P4.1(TRAAK).

Chemical Information
Molecular Weight 295.78
Formula C14H14ClNO2S
CAS Number 298684-44-3
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lianne Pope, et al. Adv Exp Med Biol. The Polysite Pharmacology of TREK K2P Channels

[2] Marco Lolicato, et al. Nature. K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site

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  Catalog
Abmole Inhibitor Catalog




Keywords: ML402  supplier, Potassium Channel, inhibitors, activators

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