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ML-184 (CID2440433) is a selective GPR55 agonist with an EC50 of 250 nM and exhibits >100-fold selectivity for GPR55 over GPR35, CB1 and CB2. ML-184(CID2440433) increases proliferation of neural stem cells and promotes neuronal differentiation in vitro. ML-184 induces phosphorylation of ERK1/2 and translocation of PKCβII to the plasma membrane by activating GPR55.
| Molecular Weight | 470.63 |
| Formula | C25H34N4O3S |
| CAS Number | 794572-10-4 |
| Solubility (25°C) | DMSO 10 mg/mL DMF 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related GPR/FFAR Products |
|---|
| GPR84 antagonist 8
GPR84 antagonist 8 is a selective GPR84 antagonist. |
| ML191
ML-191 is an antagonist of GPR55. |
| CID1172084
CID1172084 is a selective GPR55 agonist (EC50=0.16 μM). |
| ML 145
ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM. |
| PSN 375963 hydrochloride
PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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