All AbMole products are for research use only, cannot be used for human consumption.
MeTC7 is a Vitamin-D receptor (VDR) antagonist. MeTC7 has potent VDR inhibition activity with an IC50 value of 2.9 μM. MeTC7 shows good antitumor effects.
| Molecular Weight | 618.65 |
| Formula | C32H48BrN3O4 |
| CAS Number | 1817841-22-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 16.67 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Negar Khazan, et al. Cancers (Basel). Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1
| Related Vitamin Products |
|---|
| TEI-9647
TEI-9647 is a Vitamin D3 Lactone analogue, and it is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 blocks both 1α,25(OH)2D3-mediated HL-60 cell differentiation and also activation of the luciferase reporter in COS-7 cells that has been transfected with the cDNA containing the DRE of the rat 25(OH)D3-24-hydroxylase gene and cDNA of the human vitamin D nuclear receptor. |
| Menaquinone-7
Menaquinone-7 (Vitamin K2-7) belongs to a class of K2-vitamin homologs (orally active), it is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 (Vitamin K2, MK-7) inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. |
| Liarozole
Liarozole (R75251) is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of retinoic acid (IC50=7 μM). |
| VDR agonist 2
VDR agonist 2 is a VDR (vitamin D receptor) agonist that can effectively inhibit TGF-β1-induced activation of hepatic stellate cells (HSC). |
| Atocalcitol
Atocalcitol, a vitamin D3 analogue, is used in the study for psoriasis. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
