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Metapramine

Cat. No. M31234

All AbMole products are for research use only, cannot be used for human consumption.

Metapramine Structure

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Quality Control & Documentation
Biological Activity

Metapramine (19560 RP) is an antidepressant agent, inhibits norepinephrine reuptake, without affecting the reuptake of serotonin or dopamine. Metapramine is a low-affinity antagonist of the N-methyl-D-aspartic acid (NMDA) receptor complex channel.

Chemical Information
Molecular Weight 238.33
Formula C16H18N2
CAS Number 21730-16-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] A Boireau, et al. Neuropharmacology. The antidepressant metapramine is a low-affinity antagonist at N-methyl-D-aspartic acid receptors

[2] J P Sommadossi, et al. J Chromatogr. High-performance liquid chromatographic method for the determination of plasma and urine metapramine after dansylation

[3] C Rouquette, et al. J Anal Toxicol. Metapramine overdose: report of two cases and analytical determinations

[4] A M Bougerolle, et al. Eur J Drug Metab Pharmacokinet. Kinetics of metapramine and its demethylated metabolites after single and chronic oral administration in man

[5] M Bonierbale, et al. Encephale. [Metapramine: antidepressant and psycho-stimulant]

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Keywords: Metapramine supplier, GluR, inhibitors, activators

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