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Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research.
| Molecular Weight | 4178.95 |
| Formula | C178H286N52O50S7 |
| CAS Number | 145808-47-5 |
| Form | Solid |
| Storage | Store at ≤ -20°C, protect from light, dry, sealed |
[4] Adam Bartok, et al. Toxicon. Margatoxin is a non-selective inhibitor of human Kv1.3 K+ channels
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