Product Name: | Margatoxin |
Catalog Number: | M28492 |
CAS Number: | 145808-47-5 |
Formula: | C178H286N52O50S7 |
Molecular Weight: | 4178.95 |
Form: | Solid |
Storage: | Store at ≤ -20°C, protect from light, dry, sealed |
Chemical Structure: | ![]() |
QC Standard: | ≥99.0% |
H-NMR: | Consistent with structure |
Description: | Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |