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MAGLi 432

Cat. No. M21099

All AbMole products are for research use only, cannot be used for human consumption.

MAGLi 432 Structure

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Quality Control & Documentation
Biological Activity

MAGLi 432 is a novel, reversible inhibitor of monoacylglycerol lipase (MAGL). MAGLi 432 binds with high affinity to the MAGL active site with IC50 values of 4.2 nM (human enzyme) and 3.1 nM (mouse enzyme).

Chemical Information
Molecular Weight 463.80
Formula C22H24BrClN2O2
CAS Number 2361575-20-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Alicia M Kemble, et al. PLoS One. A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature

[2] Beatrice Severino, et al. Front Pharmacol. Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration

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  Catalog
Abmole Inhibitor Catalog




Keywords: MAGLi 432 supplier, MAGL, inhibitors, activators

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