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JW 642

Cat. No. M6853

All AbMole products are for research use only, cannot be used for human consumption.

JW 642 Structure
Size Price Availability Quantity
10mg USD 68  USD68 In stock
50mg USD 245  USD245 In stock
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Quality Control & Documentation
Biological Activity

JW 642 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor (IC50 = 3.7 nM). Displays >1000-fold selectivity for MAGL over fatty acid amide hydrolase (IC50 = 20.6 μM). Analog of JZL 195.

Chemical Information
Molecular Weight 462.39
Formula C21H20F6N2O3
CAS Number 1416133-89-5
Solubility (25°C) DMSO 46.24 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sheffler, et al. Mol Pharmacol. A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning.

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  Catalog
Abmole Inhibitor Catalog




Keywords: JW 642 supplier, MAGL, inhibitors, activators

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