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JJKK-048

Cat. No. M8689

All AbMole products are for research use only, cannot be used for human consumption.

JJKK-048 Structure
Size Price Availability Quantity
5mg USD 85  USD85 In stock
10mg USD 135  USD135 In stock
25mg USD 290  USD290 In stock
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Quality Control & Documentation
Biological Activity

JJKK-048 is a cell penetrant ultrapotent and highly selective inhibitor of monoacylglycerol lipase (MAGL) that exhibits a low cross-reactivity with other endocannabinoid targets. JJKK-048 is an irreversible inhibitor that binds to the active site S122.

Chemical Information
Molecular Weight 434.44
Formula C23H22N4O5
CAS Number 1515855-97-6
Solubility (25°C) DMSO: 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Niina Aaltonen, et al. In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048)

[2] Niina Aaltonen, et al. Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase

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  Catalog
Abmole Inhibitor Catalog




Keywords: JJKK-048 supplier, MAGL, inhibitors, activators

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