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LY2794193 

Cat. No. M29329

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LY2794193  Structure

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Quality Control & Documentation
Biological Activity

LY2794193 is a highly potent and selective mGlu3 receptor agonist (hmGlu3 Ki=0.927 nM,EC50=0.47 nM; hmGlu2 Ki=412 nM,EC50=47.5 nM).

Chemical Information
Molecular Weight 334.32
Formula C16H18N2O6
CAS Number 2173037-97-1
Form Solid
Solubility (25°C) DMSO 200 mg/mL (ultrasonic)
Water 2 mg/mL (ultrasonic and adjust pH to 14 with NaOH)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Roberta Celli, et al. Curr Neuropharmacol. mGlu3 Metabotropic Glutamate Receptors as a Target for the Treatment of Absence Epilepsy: Preclinical and Human Genetics Data

[2] James A Monn, et al. J Med Chem. Synthesis and Pharmacological Characterization of C4β-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Hi䲧瘀Ỵ瘁㧀痿羹皘的ࡍţࡍĀ�皚

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  Catalog
Abmole Inhibitor Catalog




Keywords: LY2794193  supplier, GluR, inhibitors, activators

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