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Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Lidocaine (Lignocaine) also inhibits sodium channels involving complex voltage and using dependence. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia.
| Molecular Weight | 234.34 |
| Formula | C14H22N2O |
| CAS Number | 137-58-6 |
| Solubility (25°C) | DMSO 80 mg/mL Water ≥ 5 mg/mL |
| Storage | 2-8°C, protect from light |
| Related Animal experimental anesthetics Products |
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| Orthocaine
Orthocaine is a local anesthetic agent. |
| Tolycaine
Tolycaine is an amide local anaesthetic. Tolycaine exhibits good anesthetic effects on mice. |
| Etidocaine hydrochloride
Etidocaine hydrochloride is an amino acidamide that acts as a local anesthetic with fast onset and long-acting properties. |
| Lidocaine N-ethyl bromide
Lidocaine N-ethyl bromide is a blocker of non-membrane-permeable,and Inhibits Acid-Induced Activation of Esophageal Nociceptive C Fiber Neurons. |
| MS-222
Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures. |
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