Free shipping on all orders over $ 500

Liarozole

Cat. No. M54837

All AbMole products are for research use only, cannot be used for human consumption.

Liarozole Structure
Synonym:

R75251

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Liarozole (R75251) is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of retinoic acid (IC50=7 μM).

Chemical Information
Molecular Weight 308.76
Formula C17H13ClN4
CAS Number 115575-11-6
Form Solid
Solubility (25°C) DMSO 90 mg/mL
Storage 4°C, protect from light
Related Vitamin Products
TEI-9647

TEI-9647 is a Vitamin D3 Lactone analogue, and it is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 blocks both 1α,25(OH)2D3-mediated HL-60 cell differentiation and also activation of the luciferase reporter in COS-7 cells that has been transfected with the cDNA containing the DRE of the rat 25(OH)D3-24-hydroxylase gene and cDNA of the human vitamin D nuclear receptor.

Menaquinone-7

Menaquinone-7 (Vitamin K2-7) belongs to a class of K2-vitamin homologs (orally active), it is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 (Vitamin K2, MK-7) inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats.

VDR agonist 2

VDR agonist 2 is a VDR (vitamin D receptor) agonist that can effectively inhibit TGF-β1-induced activation of hepatic stellate cells (HSC).

Atocalcitol

Atocalcitol, a vitamin D3 analogue, is used in the study for psoriasis.

Elocalcitol

Elocalcitol (BXL-628) is a selective, orally active vitamin D receptor (VDR) agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells.

  Catalog
Abmole Inhibitor Catalog




Keywords: Liarozole, R75251 supplier, Vitamin, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.