Free shipping on all orders over $ 500

Latrunculin A

Cat. No. M6896

All AbMole products are for research use only, cannot be used for human consumption.

Latrunculin A Structure
Synonym:

LAT-A

Size Price Availability
100ug USD 480  USD480 3-4 Weeks
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Latrunculin A (Latrunculia magnifica) is A toxin obtained from the Red Sea sponge Latrunculia magnifica that binds to actin monocytes and inhibits actin aggregation, inhibiting atP-actin, ADP-pi-actin, Kd values of ADP-actin and G-actin were 0.1, 0.4, 4.7 μM and 0.19 μM, respectively.

Product Citations
Chemical Information
Molecular Weight 421.55
Formula C22H31NO5S
CAS Number 76343-93-6
Form Liquid
Solubility (25°C) DMSO 4.22 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Pinna, et al. Neuropharmacology. A new ethyladenine antagonist of adenosine A2A receptors: Behavioral and biochemical characterization as an antiparkinsonian drug.

Related Actin-Related Protein Products
EG-011

EG-011 is a first-in-class, potent Wiskott-Aldrich Syndrome Protein (WASP) activator that activates the self-inhibited form of WASP via strong actin polymerization.In addition, EG-011 has selective anti-lymphoma activity.

Dihydrocytochalasin B

Dihydrocytochalasin B is a Cytokinesis inhibitor and changes the morphology of the cells, similar to that of cytochalasin B.

Cytochalasin B

Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with Kd value of 1.4-2.2 nM for F-actin.

Jasplakinolide

Jasplakinolide is an actin-specific reagent that promotes actin polymerization and stabilizes actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity.

Cytochalasin D

Cytochalasin D (Zygosporin A) is a cytopermeable actin polymerization inhibitor derived from fungi, which inhibits g-actin -- Cofilin interaction by binding g-actin. Cytochalasin D can also inhibit the binding of Cofilin to F-actin, reduce the release of exosomes and induce YAP phosphorylation.

  Catalog
Abmole Inhibitor Catalog




Keywords: Latrunculin A, LAT-A supplier, Actin-Related Protein, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.