Kushenol C

Cat. No. M39189

All AbMole products are for research use only, cannot be used for human consumption.

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Quality Control & Documentation

Purity: >98.0%
COA
MSDS

Product Information

Biological Activity

Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC50 of 5.45 µM.

Chemical Information

Molecular Weight	438.47
Formula	C25H26O7
CAS Number	99119-73-0
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Tao Liu et al. Cancer Med. Flavonoid extract Kushenol a exhibits anti-proliferative activity in breast cancer cells via suppression of PI3K/AKT/mTOR pathway

[2] Byoung Ok Cho et al. Molecules. Kushenol C Prevents Tert-Butyl Hydroperoxide and Acetaminophen-Induced Liver Injury

[3] Byoung Ok Cho et al. Molecules. In vitro Anti-Inflammatory and Anti-Oxidative Stress Activities of Kushenol C Isolated from the Roots of Sophora flavescens

[4] Hao Chen et al. Molecules. A Novel Flavonoid Kushenol Z from Sophora flavescens Mediates mTOR Pathway by Inhibiting Phosphodiesterase and Akt Activity to Induce Apoptosis in Non-Small-Cell Lung Cancer Cells

[5] Jang Hoon Kim et al. J Enzyme Inhib Med Chem. Kushenol A and 8-prenylkaempferol, tyrosinase inhibitors, derived from Sophora flavescens

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Kushenol C

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