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JWG-071 is the first reported kinase-selective chemical probe for ERK5, inhibits ERK5 and LRRK2 with IC50 of 88 and 109 nM, respectively. JWG-071 improves ERK5 activity and BRD4 selectivity.
| Molecular Weight | 612.76 |
| Formula | C34H44N8O3 |
| CAS Number | 2250323-50-1 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related ERK Products |
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| ERK Inhibitor II (Negative control)
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PACAP-38 (31-38), human, mouse, rat is a PAC1 receptor activator and increases the α-secretase activity. |
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Endothelin-1 (1-31) (Human) is a potent vasoconstrictor and hypertensive agent. |
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