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Ravoxertinib (GDC-0994) is an orally active ERK kinase inhibitor with IC50 of 6.1 nM and 3.1 nM against ERK1 and ERK2, respectively.
Molecular Weight | 439.85 |
Formula | C21H18ClFN6O2 |
CAS Number | 1453848-26-4 |
Solubility (25°C) | DMSO ≥ 30 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Robert Roskoski Jr. Targeting ERK1/2 protein-serine/threonine kinases in human cancers
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