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IW927 

Cat. No. M30032

All AbMole products are for research use only, cannot be used for human consumption.

IW927  Structure

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Quality Control & Documentation
Biological Activity

IW927 is a potent small molecule antagonist that blocks the binding of TNF-α to TNFRc1 with an IC50 value of 50 nM and disrupts TNFα-induced IκB phosphorylation with an IC50 value of 600 nM.

Chemical Information
Molecular Weight 441.57
Formula C22H23N3O3S2
CAS Number 389142-48-7
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] P H Carter, et al. Proc Natl Acad Sci U S A. Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-alpha

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  Catalog
Abmole Inhibitor Catalog




Keywords: IW927  supplier, TNF Receptor, inhibitors, activators

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