Free shipping on all orders over $ 500

GSK2593074A

Cat. No. M13394

All AbMole products are for research use only, cannot be used for human consumption.

GSK2593074A Structure
Synonym:

GSK'074

Size Price Availability
5mg USD 350  USD350 Out of stock
10mg USD 550  USD550 Out of stock
50mg USD 1650  USD1650 Out of stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

GSK2593074A is a necroptosis inhibitor that inhibits RIP1 and 3.

Chemical Information
Molecular Weight 465.57
Formula C27H23N5OS
CAS Number 1337531-06-2
Solubility (25°C) DMSO : 41.67 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mitri K Khoury, et al. JVS Vasc Sci. GSK2593074A blocks progression of existing abdominal aortic dilation

[2] Ting Zhou, et al. Cell Death Dis. Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models

Related RIPK Products
RIP1/RIP3/MLKL activator 1

RIP1/RIP3/MLKL activator 1 is a potent, blood-brain barrier permeable anti-glioma agent. RIP1/RIP3/MLKL activator 1 induces necroptosis through RIP1/RIP3/MLKL pathway.

Oditrasertib 

Oditrasertib is a receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC50 value lower than 100 nM.

OD36 hydrochloride 

OD36hydrochloride is a RIPK2 inhibitor with an IC50 of 5.3 nM.

RIPK1-IN-12

RIPK1-IN-12 is a potent RIPK1 inhibitor.

DNL747

DNL747 is an ASK1 and RIPK1 inhibitor for studies related to Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis.

  Catalog
Abmole Inhibitor Catalog




Keywords: GSK2593074A, GSK'074 supplier, RIPK, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.