About 10 results found for searched term "RIPK" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13405 | RIPK3-IN-1 | RIPK |
| RIPK3-IN-1 is a RIPK3 TYPE II DFG-out inhibitor with IC50 of 9.1 nM. RIPK3-IN-1 inhibited ABL, BRAF/V599E, MAP4K3 and SRC with IC50 values of 0.37, 0.15, 0.012 and 0.075 μM, respectively. | ||
| M21564 | RIPK1-IN-7 | RIPK |
| Ripk1-in-7 is a receptor interacting protein kinase 1 (RIPK1) inhibitor with Kd value of 4 nM and IC50 value of 11 nM. RIPK1-IN-7 showed good antimetastatic activity in experimental B16 melanoma lung metastasis model. | ||
| M21565 | RIPK1-IN-10 | RIPK |
| Ripk1-in-10 is a potent inhibitor of RIPK1. | ||
| M21566 | RIPK1-IN-4 | RIPK |
| RIPK1-IN-4 is a potent type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to the inactive form of RIP1 in D1-out. For RIP1 and ADP-Glo kinases, IC50 was 16 nM and 10 nM, respectively. | ||
| M28878 | PROTAC RIPK degrader-2 | PROTAC |
| PROTAC RIPK degrader-2 is a nonpeptidic PROTAC based on von Hippel-Lindau ligand which potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation. | ||
| M29295 | RIPK-IN-4 | RIPK |
| RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM. | ||
| M29760 | RIPK3-IN-2 | RIPK |
| RIPK3-IN-2 is a RIP3 inhibitor. RIPK3-IN-2 can be used in diseases caused by or associate with activated necrotic pathways research. | ||
| M41365 | RIPK2/3-IN-1 | RIPK |
| RIPK2/3-IN-1 is a potent dual RIPK2/3 kinases inhibitor with IC50 values of 3 nM and 117 nM, respectively. | ||
| M41369 | RIPK2-IN-3 | RIPK |
| RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor. | ||
| M53369 | RIPK1-IN-12 | RIPK |
| RIPK1-IN-12 is a potent RIPK1 inhibitor. | ||
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