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Golimumab

Cat. No. M25227

All AbMole products are for research use only, cannot be used for human consumption.

Golimumab Structure
Synonym:

CNTO-148

Size Price Availability
1mg USD 360  USD360 3-4 Weeks
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Quality Control & Documentation
Biological Activity

Golimumab (CNTO-148) is a potent human IgG1 TNFα antagonist monoclonal antibody. Golimumab has anti-inflammation activitity and inhibits IL-6 and IL-1β production. Golimumab acts via targeting and neutralizing TNF to prevent inflammation and destruction of cartilage and bone. Golimumab has the anticancer activity and induces cell apoptosis. Golimumab can be used for rheumatoid arthritis, Crohn's disease and cancer research.

Chemical Information
CAS Number 476181-74-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Nikhil Agrawal, et al. Am J Ther. Golimumab-Associated Glomerulonephritis

[2] Ana Teresa Melo, et al. Hum Vaccin Immunother. Golimumab (anti-TNF monoclonal antibody): where we stand today

[3] Teresa Quattrin, et al. N Engl J Med. Golimumab and Beta-Cell Function in Youth with New-Onset Type 1 Diabetes

[4] Taichi Hayashi. Nihon Rinsho. [Golimumab]

[5] Sohini Mazumdar, et al. MAbs. Golimumab

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Keywords: Golimumab, CNTO-148 supplier, TNF Receptor, inhibitors, activators

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