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Gemzil is a PPAR-α activator, which is a lipid-lowering agent. Gemfibrozil is also a nonselective inhibitor of P450, with Ki values of 5.8, 24,69 and 82 μM for CYP2C9, 2C19, 2C8 and 1A2, respectively.
| Molecular Weight | 250.33 |
| Formula | C15H22O3 |
| CAS Number | 25812-30-0 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Aleksi Tornio, et al. Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters
[2] Barbara S Wiggins, et al. Gemfibrozil in Combination with Statins-Is It Really Contraindicated?
[3] No authors listed. IARC Monogr Eval Carcinog Risks Hum. Gemfibrozil
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