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Furaltadone hydrochloride

Cat. No. M2716
Furaltadone hydrochloride Structure
Size Price Availability Quantity
100mg USD 50  USD50 In stock
500mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Furaltadone hydrochloride is an antibacterial and has distinct curative effect in the treatment of coccidiosis.

Chemical Information
Molecular Weight 360.75
Formula C13H16N4O6.HCl
CAS Number 3759-92-0
Form Solid
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] R Iglesias, et al. Antiprotozoals effective in vitro against the scuticociliate fish pathogen Philasterides dicentrarchi

[2] S Khalil, et al. AAS and AES determination of furaltadone, methadone and trazodone in pharmaceutical formulations

[3] T H Eleazer, et al. Furaltadone hydrochloride in treatment of avian vibrionic hepatitis and chronic respiratory disease complex in chickens

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