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Flecainide hydrochloride 

Cat. No. M30310

All AbMole products are for research use only, cannot be used for human consumption.

Flecainide hydrochloride  Structure

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Quality Control & Documentation
Biological Activity

Flecainide hydrochloride is a potent and orally active antiarrhythmic agent. Flecainide hydrochloride blocks the cardiac fast inward Na+ current (INa) and the rapid component of the delayed rectifier K+ current. Flecainide hydrochloride prolongs the action potential duration (APD) in ventricular and atrial muscle fibres. Flecainide hydrochloride has the potential for the research of fetal tachycardias.

Chemical Information
Molecular Weight 450.8
Formula C17H21ClF6N2O3
CAS Number 57415-44-8
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Richard A Brown, et al. Expert Opin Pharmacother. Vernakalant hydrochloride to treat atrial fibrillation

[2] Desmond Padhi, et al. Clin Pharmacokinet. Clinical pharmacokinetic and pharmacodynamic profile of cinacalcet hydrochloride

[3] L V Allen Jr, et al. Am J Health Syst Pharm. Stability of baclofen, captopril, diltiazem hydrochloride, dipyridamole, and flecainide acetate in extemporaneously compounded oral liquids

[4] S L Chase, et al. Clin Pharm. Encainide hydrochloride and flecainide acetate: two class 1c antiarrhythmic agents

[5] R J Myerburg, et al. Circulation. Reversal of proarrhythmic effects of flecainide acetate and encainide hydrochloride by propranolol

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