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Fenofibric acid

Cat. No. M5641
Fenofibric acid Structure
Synonym:

NSC 281318, Trilipix, FNF acid

Size Price Availability Quantity
500mg USD 30  USD30 In stock
1g USD 40  USD40 In stock
5g USD 100  USD100 In stock
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Quality Control & Documentation
Biological Activity

Fenofibric acid is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.

Product Citations
Chemical Information
Molecular Weight 318.75
Formula C17H15ClO4
CAS Number 42017-89-0
Solubility (25°C) 63 mg/mL in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Quesada L, et al. J Anal Toxicol. Fenofibric Acid Can Cause False-Positive Urine Methylenedioxymethamphetamine Immunoassay Results.

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Keywords: Fenofibric acid, NSC 281318, Trilipix, FNF acid supplier, PPAR, inhibitors, activators


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