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Direct Blue 1

Cat. No. M29729

All AbMole products are for research use only, cannot be used for human consumption.

Direct Blue 1 Structure
Synonym:

Chicago Sky Blue 6B

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Quality Control & Documentation
Biological Activity

Direct Blue 1 (Chicago Sky Blue 6B) is a counterstain for background autofluorescence in immunofluorescence histochemistry. Direct Blue 1, structurally related to glutamate, is a potent and competitive VGLUT inhibitor without affecting plasma membrane transporters. Direct Blue 1 is the first small molecule PrP ligand capable of inhibiting Aβ binding.

Chemical Information
Molecular Weight 992.8
Formula C34H24N6Na4O16S4
CAS Number 2610-05-1
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Water 2.08 mg/mL (ultrasonic)
Storage 4°C, protect from light, dry, sealed
References

[1] Joo-Ok Min, et al. Mol Brain. Chicago sky blue 6B inhibits α-synuclein aggregation and propagation

[2] A S Arun Prasad, et al. J Hazard Mater. Biotransformation of Direct Blue 1 by a moderately halophilic bacterium Marinobacter sp. strain HBRA and toxicity assessment of degraded metabolites

[3] R M Mohamed, et al. J Nanosci Nanotechnol. Nano Cu metal doped on TiO2-SiO2 nanoparticle catalysts in photocatalytic degradation of direct blue dye

[4] Gülay Bayramoğlu, et al. J Hazard Mater. Biosorption of benzidine based textile dyes "Direct Blue 1 and Direct Red 128" using native and heat-treated biomass of Trametes versicolor

[5] A Kai, et al. Int J Biol Macromol. Influence of substituent of direct dye having bisphenylenebis(azo) skeletal structure on structure of nascent cellulose produced by Acetobacter xylinum [I]: different influence of direct red 28, blue 1 and 15 on nascent structure

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Keywords: Direct Blue 1, Chicago Sky Blue 6B supplier, Amyloid, inhibitors, activators

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