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Dibenzoylmethane

Cat. No. M27939

All AbMole products are for research use only, cannot be used for human consumption.

Dibenzoylmethane Structure

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Quality Control & Documentation
Biological Activity

Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2.

Chemical Information
Molecular Weight 224.26
Formula C15H12O2
CAS Number 120-46-7
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fernanda Rodrigues Nascimento, et al. Chem Biol Interact. Dibenzoylmethane derivative inhibits melanoma cancer in vitro and in vivo through induction of intrinsic and extrinsic apoptotic pathways

[2] Junxiao Wang, et al. J Org Chem. Investigations on the Photochemical Reaction Mechanisms of Selected Dibenzoylmethane Compounds

[3] Deepal Vora, et al. AAPS PharmSciTech. Characterization and Systemic Delivery of Dibenzoylmethane via the Intranasal Route

[4] Eun Soo Lee, et al. J Endocrinol. Dibenzoylmethane ameliorates lipid-induced inflammation and oxidative injury in diabetic nephropathy

[5] Jutta Kockler, et al. Profiles Drug Subst Excip Relat Methodol. Butyl methoxy dibenzoylmethane

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  Catalog
Abmole Inhibitor Catalog




Keywords: Dibenzoylmethane supplier, Keap1-Nrf2, inhibitors, activators

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