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DHODH-IN-16

Cat. No. M54613

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DHODH-IN-16 Structure

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Quality Control & Documentation
Biological Activity

DHODH-IN-16 is a potent dihydroorotic acid dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH.

Chemical Information
Molecular Weight 436.00
Formula C24H25FN4O3
CAS Number 2511248-11-4
Form Solid
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related DHODH Products
DHODH-IN-13

DHODH-IN-13 is a hydroxyfurazan analog of A771726 and a dihydroorotic acid dehydrogenase (DHODH) inhibitor with an IC50 of 4.3 μM for hepatic DHODH in rats.DHODH-IN-13 can be used in rheumatoid arthritis-related studies.

DHODH-IN-12

DHODH-IN-12 is a Leflunomide derivative and a weak inhibitor of dihydroorotic acid dehydrogenase (DHODH), with a pKa of 5.07.

hDHODH-IN-5

hDHODH-IN-5 is a human dihydroorotic acid dehydrogenase (DHODH) inhibitor with an IC50 of 0.91 μM. hDHODH-IN-7 induces differentiation of acute myeloid leukemia cells.

DHODH-IN-8

DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotic acid dehydrogenase (DHODH) with IC50s of 0.13 μM and 47.4 μM and Ki of 0.016 μM and 5.6 μM, respectively.DHODH-IN-8 exhibits antimalarial activity.

DHODH-IN-14

DHODH-IN-14 is a hydroxyfurazan analog of A771726 and a dihydroorotic acid dehydrogenase (DHODH) inhibitor with an IC50 of 0.49 μM for hepatic DHODH in rats.DHODH-IN-14 can be used in rheumatoid arthritis-related studies.

  Catalog
Abmole Inhibitor Catalog




Keywords: DHODH-IN-16 supplier, DHODH, inhibitors, activators

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