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Teriflunomide is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.
Another CAS# 108605-62-5
| Molecular Weight | 270.21 |
| Formula | C12H9F3N2O2 |
| CAS Number | 163451-81-8 |
| Solubility (25°C) | DMSO 27 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Stephen L Hauser, et al. Ofatumumab versus Teriflunomide in Multiple Sclerosis
[3] No authors listed. Teriflunomide
[4] No authors listed. Teriflunomide
[5] Amit Bar-Or, et al. Teriflunomide and its mechanism of action in multiple sclerosis
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