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Dansyl chloride

Cat. No. M39660

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Dansyl chloride Structure

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Quality Control & Documentation
Biological Activity

Dansyl chloride is a reagent that reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green-fluorescent sulfonamide adducts. Dansyl chloride is widely used to modify amino acids; specifically, protein sequencing and amino acid analysis. It can also be used to label hydroxyl and carboxylic acid functional groups.

Chemical Information
Molecular Weight 269.75
Formula C12H12ClNO2S
CAS Number 605-65-2
Form Solid
Solubility (25°C) DMSO 4 mg/mL (ultrasonic and warming)
Storage 4°C, protect from light, sealed
References

[1] Chen Son Yue et al. J Food Sci. Determination of biogenic amines in chicken, beef, and mutton by dansyl chloride microwave derivatization in Malaysia

[2] Hsiu-Chuan Chen et al. J Pharm Biomed Anal. Development of a rapid and sensitive LC-MS/MS assay for the quantification of commonly abused drugs in Asia in a micro-segment of a single hair using microwave-assisted extraction and dansyl chloride derivatization

[3] Cuicui Guo et al. J Sep Sci. The dose effect of dansyl chloride on the derivative products of bisphenols and its application for the determination of bisphenols in human serum by high-performance liquid chromatography-tandem mass spectrometry

[4] K J Hunter. Methods Mol Biol. A dansyl chloride-HPLC method for the determination of polyamines

[5] Y Uratani. J Bacteriol. Dansyl chloride labeling of Pseudomonas aeruginosa treated with pyocin R1: change in permeability of the cell envelope

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