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CRBN-6-5-5-VHL is a potent and selective von Hippel-Lindau-based cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3.
| Molecular Weight | 972.2 |
| Formula | C51H69N7O10S |
| CAS Number | 2362575-45-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 113.33 mg/mL (ultrasonic) |
| Storage | -20°C, dry, sealed |
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