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Collagen Type II, Bovine

Cat. No. M49923
Collagen Type II, Bovine Structure
Size Price Availability Quantity
100mg USD 30  USD30 In stock
500mg USD 60  USD60 In stock
1g USD 90  USD90 In stock
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Quality Control & Documentation
Biological Activity

Collagen Type II, Bovine is a protein used to treat osteoarthritis. Collagen Type II shows significant efficacy in improving the pain and inflammation of collagen induced arthritis in mice.

Chemical Information
CAS Number 9007-34-5
Solubility (25°C) Water 50 mg/mL
Storage 2-8°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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Keywords: Collagen Type II, Bovine supplier, Animal Modeling, inhibitors, activators


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