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cis-Resveratrol (cis-RESV, cRes, (Z)-Resveratrol) is the Cis isomer of Resveratrol. Resveratrol is a natural phenolic compound with anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol is an inhibitor of pregnane X receptor (PXR) and an activator of Nrf2 and SIRT1 and may induce apoptosis. Resveratrol also inhibits a wide spectrum of targets including 5-lipoxygenase (LOX), cyclooxygenase (COX), IKKβ, DNA polymerases α and δ with IC50 of 2.7 μM, <1 μM, 1 μM, 3.3 μM and 5 μM, respectively.
Molecular Weight | 228.24 |
Formula | C14H12O3 |
CAS Number | 61434-67-1 |
Solubility (25°C) | DMSO 46 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Boxu Ren, et al. Cancer Lett. Resveratrol for cancer therapy: Challenges and future perspectives
[3] Johannes M Breuss, et al. Int J Mol Sci. Resveratrol and Its Effects on the Vascular System
[4] Ritu Kataria, et al. Curr Top Med Chem. Resveratrol in Various Pockets: A Review
[5] Sabina Galiniak, et al. Acta Biochim Pol. Health benefits of resveratrol administration
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