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CHIR-98023 is a potent, selective and reversible inhibitor of GSK3, with IC50s of 10 nM and 6.7 nM for GSK3α and GSK3β, respectively. CHIR-98023 can improve insulin action and glucose metabolism.
| Molecular Weight | 471.3 |
| Formula | C20H16Cl2N8O2 |
| CAS Number | 252916-76-0 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Phospho-Glycogen Synthase Peptide-2 (substrate) is peptide substrate for glycogen synthase kinase-3 (GSK-3) and can be used for affinity purification of protein-serine kinases. |
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ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC50 value of 71 nM for GSK-3β. |
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Products are for research use only. Not for human use. We do not sell to patients.
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