Product Name: | CHIR-98023 |
Catalog Number: | M29694 |
CAS Number: | 252916-76-0 |
Formula: | C20H16Cl2N8O2 |
Molecular Weight: | 471.3 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Chemical Structure: | ![]() |
QC Standard: | ≥99.0% |
H-NMR: | Consistent with structure |
Description: | CHIR-98023 is a potent, selective and reversible inhibitor of GSK3, with IC50s of 10 nM and 6.7 nM for GSK3α and GSK3β, respectively. CHIR-98023 can improve insulin action and glucose metabolism. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |