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Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity. Chebulinic acid reduce the expression and activity of MMP-2 at an ED50 value of 100 μM. Chebulinic acid significantly inhibited H+ K+-ATPase activity in vitrowith IC50 of 65.01 μg/ml.
| Molecular Weight | 956.68 |
| Formula | C41H32O27 |
| CAS Number | 18942-26-2 |
| Solubility (25°C) | DMSO 10 mM |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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