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Carubicin hydrochloride

Cat. No. M30244

All AbMole products are for research use only, cannot be used for human consumption.

Carubicin hydrochloride Structure
Synonym:

Carminomycin hydrochloride; Carminomicin I hydrochloride

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Quality Control & Documentation
Biological Activity

Carubicin hydrochloride is a microbially-derived compound. Carubicin hydrochloride is an effective inhibitor of VHL-defective (VHL−/−) CCRCC cell proliferation. Carubicin hydrochloride also induces apoptosis by a mechanism independent of p53 or hypoxia-inducible factor HIF2. Carubicin hydrochloride has the potential for the research of cancer diseases.

Chemical Information
Molecular Weight 549.95
Formula C26H28ClNO10
CAS Number 52794-97-5
Form Solid
Solubility (25°C) DMSO 62.5 mg/mL (ultrasonic)
Storage 4°C, dry, sealed
References

[1] C Monneret. Eur J Med Chem. Recent developments in the field of antitumour anthracyclines

[2] M Ogawa, et al. Gan To Kagaku Ryoho. [New anthracyclines]

[3] R C Young, et al. N Engl J Med. The anthracycline antineoplastic drugs

[4] A Aboud, et al. Cancer. Carminomycin. A new anthracycline analog in the treatment of advanced breast cancer

[5] F M Muggia, et al. Crit Rev Oncol Hematol. New anthracycline antitumor antibiotics

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Keywords: Carubicin hydrochloride, Carminomycin hydrochloride; Carminomicin I hydrochloride supplier, Apoptosis, inhibitors, activators

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