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Bupivacaine is a NMDA receptor inhibitor. Bupivacaine can block sodium, L-calcium, and potassium channels. Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain. Bupivacaine acts by binding to the intracellular portion of voltage-gated sodium channels and blocking sodium influx into nerve cells.
| Molecular Weight | 288.43 |
| Formula | C18H28N2O |
| CAS Number | 2180-92-9 |
| Solubility (25°C) | methanol 10 mg/mL chloroform 10 mg/mL |
| Storage | 2-8°C, dry, sealed |
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