Free shipping on all orders over $ 500

Brivudine

Cat. No. M7515

All AbMole products are for research use only, cannot be used for human consumption.

Brivudine Structure
Synonym:

BVDU

Size Price Availability Quantity
10mM*1mL in DMSO USD 41  USD41 In stock
10mg USD 30  USD30 In stock
25mg USD 40  USD40 In stock
50mg USD 55  USD55 In stock
100mg USD 73  USD73 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Brivudine is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. It is incorporated into the viral DNA and blocks the action of DNA polymerases, thus inhibiting viral replication.

Product Citations
Chemical Information
Molecular Weight 333.14
Formula C11H13BrN2O5
CAS Number 69304-47-8
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hew K, et al. PLoS One. Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of Brivudine.

[2] Gonen I, et al. J Chemother. Brivudin induced delirium: a case report.

Related DNA/RNA Synthesis Products
GSK4418959

GSK4418959 (IDE275) is a non-covalent, reversible, selective and orally active WRN helicase inhibitor. GSK4418959 inhibits ATPase and DNA unwinding functions in an ATP-competitive manner.

Dencatistat

Dencatistat (P115) is an inhibitor of Cytidine Triphosphate Synthase 1 (CTPS1) with an IC50 value of ≤ 0.1 μM.

Antipain dihydrochloride

Antipain dihydrochloride is a protease inhibitor. Antipain dihydrochloride inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride also restricts uterine DNA synthesis and function in mice.

Tetrahydrouridine

Tetrahydrouridine (THU) is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine.

Crisnatol

Crisnatol (BWA770U) is a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells. Crisnatol (BWA770U) is also an orally active and anticancer agent.

  Catalog
Abmole Inhibitor Catalog




Keywords: Brivudine, BVDU supplier, DNA/RNA Synthesis, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.