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BMS-986163 

Cat. No. M28872

All AbMole products are for research use only, cannot be used for human consumption.

BMS-986163  Structure

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Quality Control & Documentation
Biological Activity

BMS-986163 is a negative allosteric modulator of GluN2B. The proagent BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).

Chemical Information
Molecular Weight 462.45
Formula C23H28FN2O5P
CAS Number 1801151-09-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Lawrence R Marcin, et al. ACS Med Chem Lett. BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive Disorder

[2] Linda J Bristow, et al. J Pharmacol Exp Ther. Preclinical Characterization of ( R)-3-((3 S,4 S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in䲧瘀Ỵ瘁㧀痿羹皘

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  Catalog
Abmole Inhibitor Catalog




Keywords: BMS-986163  supplier, GluR, inhibitors, activators

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