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BMS-687453

Cat. No. M5125

All AbMole products are for research use only, cannot be used for human consumption.

BMS-687453 Structure
Size Price Availability Quantity
10mM*1mL in DMSO USD 120 In stock
5mg USD 110 In stock
10mg USD 180 In stock
25mg USD 350 In stock
50mg USD 540 In stock
100mg USD 840 In stock
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Quality Control & Documentation
Biological Activity

Bms-687453 is an effective and selective PPARα agonist with EC50 and IC50 of 10 nM and 260 nM for human PPARα, respectively. The EC50 and IC50 values were 4100 nM and >15000 nM, respectively.

Chemical Information
Molecular Weight 444.86
Formula C22H21ClN2O6
CAS Number 1000998-59-3
Form Solid
Solubility (25°C) DMSO > 31 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Li J,et.al. J Med Chem. Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453).

[2] Vassallo JD,et.al. Toxicol Sci. Biomarkers of drug-induced skeletal muscle injury in the rat: troponin I and myoglobin.

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