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β-Amyloid (22-35) (TFA)

Cat. No. M31062

All AbMole products are for research use only, cannot be used for human consumption.

β-Amyloid (22-35) (TFA) Structure
Synonym:

Amyloid β-Protein (22-35) (TFA)

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Quality Control & Documentation
Biological Activity

β-Amyloid 22-35 (Amyloid β-Protein 22-35) TFA, the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 TFA forms aggregates and typical amyloid fibrils resembling those of the β-amyloid protein in neutral buffer solution.

*The compound is unstable in solutions, freshly prepared is recommended

Chemical Information
Molecular Weight 1517.64
Formula C61H103F3N16O23S
Form Solid
Solubility (25°C) Water 100 mg/mL (ultrasonic)
Storage Store at ≤ -20°C, dry, sealed
References

[1] Dominique Campion, et al. Acta Neuropathol. SORL1 genetic variants and Alzheimer disease risk: a literature review and meta-analysis of sequencing data

[2] Neda Yousefirad, et al. Int J Physiol Pathophysiol Pharmacol. Amyloid beta peptide 22-35 induces a negative inotropic effect on isolated rat hearts

[3] Coralie Di Scala, et al. Biochemistry. Interaction of Alzheimer's β-amyloid peptides with cholesterol: mechanistic insights into amyloid pore formation

[4] Bao-Quan Zhao, et al. Int J Pharm. Amelioration of dementia induced by Aβ 22-35 through rectal delivery of undecapeptide-hEGF to mouse brain

[5] T Takadera, et al. Neurosci Lett. Toxic effect of a beta-amyloid peptide (beta 22-35) on the hippocampal neuron and its prevention

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Keywords: β-Amyloid (22-35) (TFA), Amyloid β-Protein (22-35) (TFA) supplier, Amyloid, inhibitors, activators

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