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Azure A chloride

Cat. No. M42856
Azure A chloride Structure
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Biological Activity

Azure A (chloride) is a phenothiazine dye.

Chemical Information
Molecular Weight 291.8
Formula C14H14ClN3S
CAS Number 531-53-3
Form Solid
Storage 4°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ram Krishna Hona et al. Int J Mol Sci. Ionic Conductivity of K-ion Glassy Solid Electrolytes of K2S-P2S5-KOTf System

[2] Lixin Zhao et al. Mikrochim Acta. A nanozyme-based competitive electrochemical immunosensor for the determination of E-selectin

[3] Jerónimo Agrisuelas et al. Polymers (Basel). A Comparative Study of Poly(Azure A) Film-Modified Disposable Electrodes for Electrocatalytic Oxidation of H₂O₂: Effect of Doping Anion

[4] Puja Paul et al. Spectrochim Acta A Mol Biomol Spectrosc. Spectroscopic studies on the binding interaction of phenothiazinium dyes toluidine blue O, azure A and azure B to DNA

[5] P J Bennion et al. Stain Technol. The use of a basic dye (azure A or toluidine blue) plus a cationic surfactant for selective staining of RNA: a technical and mechanistic study

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