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Atopaxar hydrobromide

Cat. No. M30134

All AbMole products are for research use only, cannot be used for human consumption.

Atopaxar hydrobromide Structure
Synonym:

E5555 hydrobromide; ER 172594-06

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Quality Control & Documentation
Biological Activity

Atopaxar (E5555) hydrobromide is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar hydrobromide, an antiplatelet agent, interferes with platelet signaling. Atopaxar hydrobromide can be used for the research of atherothrombotic disease.

Chemical Information
Molecular Weight 608.54
Formula C29H39BrFN3O5
CAS Number 474550-69-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jingjie Sun, et al. Invest New Drugs. Discovery and evaluation of Atopaxar hydrobromide, a novel JAK1 and JAK2 inhibitor, selectively induces apoptosis of cancer cells with constitutively activated STAT3

[2] Motoji Kogushi, et al. Eur J Pharmacol. Oral administration of the thrombin receptor antagonist E5555 (atopaxar) attenuates intimal thickening following balloon injury in rats

[3] Motoji Kogushi, et al. Eur J Pharmacol. The novel and orally active thrombin receptor antagonist E5555 (Atopaxar) inhibits arterial thrombosis without affecting bleeding time in guinea pigs

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  Catalog
Abmole Inhibitor Catalog




Keywords: Atopaxar hydrobromide, E5555 hydrobromide; ER 172594-06 supplier, PAR, inhibitors, activators

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