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Govorestat (AT-007) is a central nervous system (CNS)-permeable aldose reductase inhibitor that prevents the conversion of glucose to sorbitol and may be used in studies related to neurological disorders.
| Molecular Weight | 425.4 |
| Formula | C17H10F3N3O3S2 |
| CAS Number | 2170729-29-8 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Aldose Reductase Products |
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| Tolrestat
Tolrestat is a potent, orally active aldose reductase inhibitor with IC50 of 35 nM. |
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AKR1C3-IN-10 is a selective AKR1C3 inhibitor (IC50=51 nM). |
| Dehydroglyasperin D
Dehydroglyasperin D inhibits rat and human Aldose Reductase (AR) (IC50: 62.4 μM and 176.2 μM respectively). |
| Ganoderic acid Df
Ganoderic acid Df is a lanostane-type triterpenoid, that can be isolated from the fruiting body of Ganoderma lucidum. |
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