Free shipping on all orders over $ 500

AOH1996

Cat. No. M40519

All AbMole products are for research use only, cannot be used for human consumption.

AOH1996 Structure
Size Price Availability Quantity
1mg USD 50  USD50 In stock
5mg USD 120  USD120 In stock
10mg USD 185  USD185 In stock
25mg USD 400  USD400 In stock
50mg USD 600  USD600 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

AOH1996 is an orally active small molecule PCNA inhibitor, which can be obtained by adding a methoxy group to the interstitial position of the benzene ring at the end of AOH1160, and enhances the interaction between PCNA and RPB1, the largest subunit of RNA polymerase II, as well as selectively kills cancer cells, which can be used in cancer-related research.

Chemical Information
Molecular Weight 426.46
Formula C26H22N2O4
CAS Number 2089314-64-5
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Long Gu et al. Cell Chem Biol. Small molecule targeting of transcription-replication conflict for selective chemotherapy

Related DNA/RNA Synthesis Products
Deoxyribonucleic Acid (from Salmon sperm)

Deoxyribonucleic Acid (from Salmon sperm) can be used as a research reagent, widely used in molecular biology, pharmacology and other scientific research.

GSK4418959

GSK4418959 (IDE275) is a non-covalent, reversible, selective and orally active WRN helicase inhibitor. GSK4418959 inhibits ATPase and DNA unwinding functions in an ATP-competitive manner.

Dencatistat

Dencatistat (P115) is an inhibitor of Cytidine Triphosphate Synthase 1 (CTPS1) with an IC50 value of ≤ 0.1 μM.

Antipain dihydrochloride

Antipain dihydrochloride is a protease inhibitor. Antipain dihydrochloride inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride also restricts uterine DNA synthesis and function in mice.

Tetrahydrouridine

Tetrahydrouridine (THU) is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine.

  Catalog
Abmole Inhibitor Catalog




Keywords: AOH1996 supplier, DNA/RNA Synthesis, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.